Fifteen Dorper (D; 3.8 mo of age, 29 kg), 14 St. Croix (C; 3.9 mo, 18 kg), 14 Kiko (K; 4.0 mo, 19 kg), 13 Boer (B; 3.2 mo, 22 kg), and 17 Spanish (S; 3.1 mo, 18 kg) males were used to investigate effects of classification for resistance to Haemonchus contortus of sire and among and within breed differences in the second year of a central test at Langston University (LU) for growth performance and response to artificial infection with infective larvae. In the first year of the test, males were randomly selected from 4 commercial farms in KS, MO, and OK and LU B and S goat herds. Animals used in this study were progeny of the sires (i.e., High and Moderate, with no progeny of susceptible males) selected in the first year. For both years, the test entailed an adjustment period of 2 wk followed by 8 wk of data collection. Animal groups were housed separately in adjacent pens with automated feeders allowing free-choice access to a 15% CP (DM) and 50% concentrate pelletized diet. During adaptation, anthelmintic treatment resulted in low fecal egg count (FEC; < 600/g), after which 10,000 larvae were administered orally. Packed cell volume (PCV) was measured weekly and FEC was determined 4 times in wk 6–8. For analysis, initial BW, PCV, and FEC were covariates, and the logarithmic transformation ln(x + 2,000) was used for mean FEC. Breed affected (P ≤ 0.01) ADG (307, 286, 159, 247, and 142 g; SEM = 13.8), DMI (2.2, 1.6, 1.3, 1.5, and 1.3 kg; SEM = 0.12), FEC (2,098, 1,278, 1,419, 1,335, and 716 eggs/g, original scale; SEM = 80.9), and PCV (27.2, 31.7, 31.6, 28.1, and 25.6% ; SEM = 0.76 for D, C, K, B, and S, respectively). Means of resistance classification of sires were similar (P > 0.10) for FEC, PCV, ADG, and DMI. Correlation coefficients of sire and progeny FEC within breed were nonsignificant (P > 0.10). In conclusion, with only one generation of selection, there was no detectable relationship in resistance to internal parasite between selected sires and progeny based on FEC after an artificial challenge with H. contortus larvae in a standardized environment.