Quaternary benzophenanthridine alkaloids and protopine alkaloids (QBA + PA) have systemic anti-inflammatory effects. However, its activity against nematode parasites of the gastro intestinal tract is not well documented. In the actual experiment, 20 receiving bull-calves 236 ± 4.12 kg were utilized to evaluate the influence of a standardized QBA + PA Papaveraceae family plant preparation named Sangrovit RS (SANG; Phytobiotics, Eltville, Germany) on fecal shedding of parasitic nematode eggs. In groups of 5, bull-calves were allotted in dirt-floor pens, fed with 70% roughage corn silage-diet. During 3 consecutive days fecal samples were taken from each animal and nematode eggs per gram of feces (EGF) were counted by McMaster method. Pens were randomly sorted to receive 10 g/d of Sangrovit RS (SANG) or not (Control) supplied on the feed bunk as top dressing. Once completed the 28 d period treatments, fecal samples were taken again during 3 consecutive days, and EGF count was performed. Results were analyzed by ANOVA for a completely randomized design. In fecal samples taken before applied treatments, the nematode EGF count was similar (P > 0.30) between treatments. After 28 d total nematode EGF was lower (P = 0.04) in the SANG group compared with the Control group (33 vs. 113 EGF). The amount of Haemonchus sp. EGF (an abomasum parasite) was lower (P = 0.05) in bull-calves fed SANG compared with Control group (12 vs. 48 EGF). The EGF count of Cooperia spp., a parasite of the small intestine, was inferior (P = 0.03) in SANG supplemented bull-calves in relationship to unsupplemented bull-calves (13 vs. 52 EGF). Results suggest that fed QBA + PA plant preparation contributes to decrease parasites nematode eggs shedding in receiving bull-calves.