Poor uterine health can be detrimental to a fresh cow’s ability to efficiently re-breed. This 2-phase study aimed to establish changes in vaginal mucus resistance as it relates to calving date and uterine health post-calving. In phase one, nulliparous heifers (n = 11) and multiparous cows (n = 21) were examined approximately 2 weeks before and the week of calving with a device designed to measure changes in electrical resistance in ohms (Ω) of cervical/cranial vaginal mucus (Draminski Estrous Detector, Poland). Three consecutive readings were taken at each time point with the average being utilized for analysis. At time of Draminski readings, urine pH, rectal temperatures, body condition scores and udder edema levels were recorded. Increasing blood-flow and uterine contractions associated before calving as the result of estrogen may change the deposition of circulating minerals in mucus, as indicated by electrical resistance, which may have an impact on the uterine environment post-calving. In phase 2, 10 heifers and 14 cows from the original groups were assessed for incidence of metritis on d 7 and 14 (±3 d) post-calving. Vaginal mucus was visually examined using the Metricheck (Simcro, New Zealand) and subjectively scored by one individual (0-clear, 1-up to 25% white or off white pus, 2–25–75% pus, 3- > 75% pus). Draminski readings averaged 183 ± 28.8Ω and 184 ± 42.8Ω for the first and second readings, respectively. The Draminski readings did not consistently increase (n = 12) or decrease (n = 15) relative to calving date. Precalving data were analyzed using the PROC GLM procedure of SAS for their relationship to postcalving mucous scores. The first model included overall increase or decrease in Draminski readings relative to calving, rectal temperature and body condition score with group (heifer or cow) held constant. The second model included the first or second Draminski reading with group held constant. There was no association between actual Draminski readings (P > 0.05) or changes in Draminski readings over time (P > 0.05) and the Metricheck scores postcalving. The lack of statistical associations was likely the result of high variability in Draminski readings.