The objective of this study was to investigate effects of 4 colostrum feeding programs on passive transfer of immunity, health, and growth performance of Holstein dairy calves before 70 d age. Experiment 1, 76 newborn Holstein calves (24 bulls and 52 heifers) were blocked by colostrum quality and sex and assigned randomly to 4 treatments. Calves were housed in individual hutches and were moved to the heifer pens at the age of 9 week. Colostrum feeding programs were as follows: calves in T₃₂₂ were fed 3 L at 0 h (birth), 2 L at 6 h, and 2 L at 12 h; calves in T₄₀₂ were fed 4 L at 0 h and 2 L at 12 h; calves in T₄₀₀ were fed 4 L only at birth; calves in T₂₂₀ were fed 2 L at 0 h and 2 L at 6 h. Blood sample collected at 24 h after birth showed that serum total protein (TP, g/dL) and IgG (mg/mL) levels were significantly higher for calves in T₃₂₂ (TP = 6.11 g/dL, IgG = 22.49 mg/mL, P < 0.01) and T₄₀₂ (TP = 5.89 g/dL, IgG = 19.99 mg/mL, P < 0.05) compared with calves in T₄₀₀ (TP = 5.56 g/dL, IgG = 16.05 mg/mL) and T220 (TP = 5.58 g/dL, IgG = 16.31 mg/mL). At 48 h after birth, serum TP and IgG levels were significantly higher for calves in T₃₂₂ (TP = 6.37 g/dL, IgG = 25.61 mg/mL, P < 0.01) and T₄₀₂ (TP = 6.12 g/dL, IgG = 22.61 mg/mL, P < 0.01) compared with calves in T₄₀₀ (TP = 5.58 g/dL, IgG = 16.30 mg/mL) and T₂₂₀ (TP = 5.66 g/dL, IgG = 17.24 mg/mL). Experiment 2, 40 heifers in experiment 1 were involved. Results showed that the incidence and frequency of diarrhea and the fecal index tended to be greater (P > 0.05) in T₄₀₀ and T₂₂₀ than in the other 2 treatments. At the first week post-weaning, calves from T₃₂₂ (1536.54 g/d, DM, P < 0.01) and T₄₀₀ (1321.23 g/d, DM, P < 0.01) had significantly higher starter intake than that of calves from T₂₂₀ (1162.01 g/d, DM). These results suggest that colostrum feeding program 322 (3 L at 0 h, 2 L at 6 h, and 2 L at 12 h) and 402 (4 L at 0 h and 2 L at 12 h) can improve passive Immunity, health, and growth performance of Holstein dairy calves compared with the other 2 feeding programs. Further research is needed to evaluate the influence of colostrum feeding programs on later growth, reproduction and lactation performance of dairy cattle.