Arid and semi-arid areas of northern Mexico are characterized for having little availability of fodder. Another limitation in some desert areas is the presence of soils with high amounts of salts, which limits the development of crops. Four-wing saltbush (Atriplex canescens) is a shrub of arid and semi-arid areas adapted to soils with high salinity, it remains green throughout the year, and has a high nutritional content, which represents a good forage for herbivores in these areas. For this study, A. canescens samples (leaves) from 20 plots (3 × 3 m) were collected during November in northern Mexico (24°N) and the nutrient content was analyzed. Soil samples near stems of these shrubs were also collected, at depths of 0–30 cm. Crude protein of this fodder shrub was 9.87%. Soil testing showed slight levels of salinity, with an electrical conductivity of 2 to 4 mMhos/cm. The association between nutrient content of Atriplex canescens and electrical conductivity of soil were analyzed by nonlinear regression with the CurveExpert program. It was found that the crude protein of A. canescens was positively affected by ascending levels of electrical conductivity (y = 10.9 × 0.092^1/x; r² = 0.17). Calcium levels increased with electrical conductivity (y = 4.85 + 0.34x – 0.32/x²; r² = 0.31). The association between electrical conductivity and phosphorous was weak (y = 7.29 −0.94x −0.5/x²; r² = 22). The variable with the highest association with electrical conductivity was potassium (r² = 0.44). It was concluded that neither dry matter digestibility nor structural carbohydrates are associated with electrical conductivity of soil and that the increase in electrical conductivity of soil mainly affect the mineral content of this fodder shrub.