Canola press-cake (CPC) is a co-product from biodiesel production in small-scale processing plants that mechanically press oil from cleaned canola seed without seed conditioning or solvent extraction. The CPC contains 37% CP and 20% remaining oil; thus, CPC could be a source of AA and energy in pig diets. However, growth responses to increasing inclusion of CPC have not been evaluated in pigs. To evaluate the feeding value of CPC, 240 pigs (7.5 kg) starting 1 wk after weaning at 19 d of age were fed 5 wheat-based diets containing 0, 5, 10, 15, or 20% CPC to replace soybean meal in 2 phases (Phase 1 and 2). Diets were formulated to contain 2.45 and 2.41 Mcal NE/kg and 5.02 and 4.20 g standardized ileal digestible (SID) Lys/Mcal NE, respectively, and were fed for 2 wk for phase 1 (d 0–14) and 3 wk for phase 2 (d 15–35). Feed added and left and pig BW were measured weekly to calculate pen ADFI, ADG, and G:F. Freshly-voided feces were collected on d 12–13 and d 33–34 for phase 1 and 2, respectively, to determine diet apparent total-tract digestibility (ATTD) of DM, GE, and CP and diet DE using the index method. The diet NE value was predicted by Eq. 1–8 in NRC (2012). Data were analyzed using the MIXED procedure in SAS by orthogonal contrasts tested the linear or quadratic effects of CPC inclusion. Increasing dietary inclusion of CPC linearly reduced (P < 0.05) the ATTD of GE by 1.3% and CP by 2.3% and diet DE and NE values in phase 1 and 2. Increasing dietary inclusion of CPC did not affect overall (d 0–35) ADFI and ADG of pigs but linearly reduced (P < 0.01) ADFI for d 29–35, linearly increased (P < 0.05) ADG for d 15–21, and linearly reduced (P < 0.05) ADG for d 29–35. Increasing CPC inclusion linearly increased (P < 0.05) feed efficiency for d 15–21 and overall. In conclusion, feeding up to 20% of CPC reduced ATTD of nutrients but did not reduce overall growth performance of weaned pigs when diets were balanced for NE and SID Lys/NE ratio. The CPC may be used as an alternative feedstuff to soybean meal to reduce feed cost while maintaining performance.