To investigate the effects of a blend of organic acids and medium chain fatty acids on gut health, 96 weaned barrows (21 d; BW 5.2 kg) were housed (3 pigs/pen) with ad libitum access to feed and water over a 28-d study. The diets were comprised primarily of corn, soybean meal and a source of lactose, with inclusion of 0, 0.15, 0.30 and 0.45% of blend (acetic acid, citric acid, formic acid, lactic acid, caprylic acid and caproic acid). For sample collection, piglets (n = 16) were euthanized at 14 and 28-d study. Two-cm segments of duodenum and jejunum were collected for the determination of villous height (VH), crypt depth (CD), villous height:crypt (VH:CD) depth ratio and count goblet cell by methods of Schiff-PAS and Alcian Blue. Images were recorded using an Olympus BX41 camera. Cell Sense standard software was used for measurement of the respective morphological aspects. For each intestinal sample, a minimum of 20 to 30 full villi and crypts were measured and in assessing the number of goblet cells, 15 counts were performed. ANOVA was generated using the mixed-model procedure of SAS. Linear, quadratic and cubic polynomials were used to detect the response to dietary inclusion of the blend. Was observed a cubic effect in duodenal VH:CD (P < 0.0001) ratio and jejunal goblet cell count (P = 0.0034) by method of Schiff-PAS at 14-d study. Was observed a cubic effect on CD (P = 0.0009), goblet cell count (P = 0.0014) by method of Schiff-PAS, goblet cell count (P = 0.006) by method of Alcian Blue, and an increasing linear effect on the VH:CD (P = 0.0006) ratio in jejunum of pigs at 28-d study. Results indicate the blend had little effect at 14-d study; however, positive effects of blend were observed at 28-d of study. In conclusion, the blend may contribute to intestinal restitution.