Have various segments of a representative sample of US consumers heard of prominent animal diseases such as bovine spongiform encephalopathy (BSE), porcine epidemic virus diarrhea (PEDV), tuberculosis (TB), chronic wasting disease (CWD), leptospirosis, rabies, and food and mouth disease (FMD)? We have found that 30% of respondents reported having heard of BSE, 17% heard of PEDV, and 27% heard of CWD. Various demographic factors have been found, through cross-tabulations, to be associated with the awareness of animal diseases. Being a college graduate, someone who regularly hunts, a pet owner, or a member of HSUS or PETA were all positively correlated with having heard of BSE, PED-v, and Leptospirosis. Reporting concern for the welfare of beef cattle, dairy cattle, or pigs was positively correlated with being aware of all diseases analyzed. Do people who have recently visited farms raising cattle, deer, or pigs show an increased awareness for their associated diseases? Having visited a beef cattle farm in the last 5 years was positively correlated with animal disease awareness. Visiting a dairy or pig farm in the past 5 years was positively associated with awareness of BSE, PED-v, CWD, and Leptospirosis. Consumers who raise their own food, either through gardening, raising chickens for eggs or meat, or raising animals for meat, are more likely to be aware of BSE and PEDV. Related to disease awareness is inspection; respondents were asked about veterinary inspection for transport. Sixty-eight percent of respondents agreed that livestock should be required to undergo a veterinary inspection before being transported within or outside the state. Likewise, 75% of US consumers who were aware of BSE agree that beef carcasses should be tested for BSE before being used for human food consumption. Understanding the demographics the predispose consumers to be more aware and sensitive to animal disease/health issues is important for animal industry communication to consumers to ensure consumer confidence in the food they choose to purchase.