Rumatel (morantel tartrate) is an FDA-approved anthelmintic safe for use in goats and has no milk withhold. The objective of this study was to evaluate the efficacy of Rumatel on the removal of gastrointestinal nematodes (GIN) in lactating dairy goats. Twenty second-lactation crossbreed does (59 – 68 kg; mean days in milk = 128.5) from a south-central Wisconsin commercial herd were used in this study. Goats were housed in a pole barn with roll-up curtain sides on a bedded pack with continual access to pasture. A complete feed pellet was provided to the does twice a day and alfalfa hay was fed ad libitum. Goats had not been dewormed for 7 mo. Fecal pellets were collected from the rectum of each doe at 2 different time points, once immediately before the administration of Rumatel and again 14 d later. Fecal samples were analyzed for GIN using the McMaster’s technique for fecal egg counts. Eligible samples [≥25 Trichostrongyle spp. eggs/gram of feces (EPG)] were further analyzed using the Peanut Agglutination test. Conjunctival examinations were conducted on all does using the FAMACHA card as a color reference (scored 1 – 5) at each fecal collection. Goats were dewormed once using Manna Pro Positive Pellet Goat Dewormer (morantel tartrate: 880 g/ton) immediately following the first fecal collection. Does were group-fed the product with enough pellet provided for each goat to consume 0.68 kg (0.66 g of morantel tartrate). Means were compared with a Student’s t-test. Feeding Rumatel resulted in significantly lower (P < 0.01) EPG of total nematodes, Trichostrongyle spp., and Haemonchus contortus. Fecal egg counts were 176.3, 167.5, and 166.1 EPG, respectively, before deworming and 20.0, 20.0, and 14.7 EPG after deworming. Rumatel treatment also lowered the percentage of goats with H. contortus infections from 74.7% to 29.6% (P = 0.001) and decreased FAMACHA scores from 3.5 to 2.65 (P = 0.001). Results indicate that Rumatel is an efficacious anthelmintic for lactating dairy goats for GIN like Trichostrongyle spp., including H. contortus.