The pituitary transcription factor (PIT1) (or POU1F1) protein belongs to pituitary-specific transcription factors localized on chromosome 13 in porcine. The PIT1 gene was used as a candidate gene for selecting animals for growth and carcass traits. Thus, the aim of this study was to identify and compare the Rsa I polymorphism of the PIT1 gene in finishing pigs to evaluate mutations in the meat quality of porcine by screening to novel gene markers PIT-1 and to investigate the genotypic alteration of the pigs, which may help to locate the chromosomal regions that may be linked with candidate genes that are associated with pig muscle growth and pork quality. The genomic DNA from 460 pigs was extracted and the genotypes for polymorphism analysis were determined using PCR-RFLP. The PIT1 genotype frequencies analyzed were 42.39% for AA, 39.13% for AB and 18.48% for BB. Several significant associations of PIT1 gene polymorphisms with some of the growth traits were observed. The pigs with BB genotype showed the highest average daily gain. Several significant differences were observed in meat color (A, B and L*; P < 0.05). Meat carcass traits LMP and LMC seem to be lower in pigs with BB genotype compared with AA genotype animals. The AA finishers presented a lower level of back fat thickness compared with AB genotypes. The PIT1 are potential candidate genes, influencing quality traits as they encode proteins, which causes essential effects in its functions and the present study tries to confirm the association of its polymorphism with its economically important traits in pigs. Therefore the assumption that genetic unpredictability of the PIT1gene could be associated with swine population in commercial traits.