This presentation provides a brief review of feedlot nutrition and management considerations for Holstein steers. Calf-fed Holstein steers typically enter the commercial feedlot at 100 to 120 d of age, with a full purchase weight of approximately 137 ± 16 kg. On a shrunk-to-shrunk basis (full purchase and final weights reduced 4%), harvest weight, ADG, and days on feed of implanted calf-fed Holstein steers average 588 ± 16 kg, 1.31 ± 16 kg, and 349 ± 10 d, respectively. Rate of gain and gain efficiency are markedly influenced by harvest weight and placement month. Due to high summer temperatures, late summer and fall close-outs are least efficient for feedlots located in the desert southwest. Calf density should be regulated to achieve an average surface moisture level of roughly 20%. Because water consumption is greater (20 to 30%) in Holsteins than conventional beef breeds, they require more pen and shade space. In commercial practice, calf-fed Holsteins are fed a single growing-finishing diet throughout the duration of the feedlot period. A characteristic diet may contain 12–13% crude protein (urea the sole source of supplemental N), 0.70–0.80% calcium, 0.35–0.40% phosphorus,0.20 to 0.28% magnesium, 0.3 to 0.4% tracemineral salt, and 8% forage NDF. Due to very high growth potential during the initial 112 d on feed, this diet will not meet the calf’s metabolizable amino acid requirements, resulting in a predictable decrease (15 to 20%) in energetic efficiency during that phase. The rather high incidence of liver abscess frequently observed among lots of calf-fed Holsteins may warrant continued low-level antibiotic supplementation. Good feedbunk management is particularly important with Holsteins. The high energy content of the diet fed over a protracted period of time poses added threat to the possibility of acidosis.